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Palmitoyl Hexapeptide - 14

What Palmitoyl Hexapeptide - 14 is & what it does

Palmitoyl Hexapeptide-14 is a synthetic peptide made of a short six-amino-acid chain bonded to palmitic acid, a fatty acid that helps it spread through an emulsion. In skincare formulas it is used as a conditioning and signaling-type active intended to support the look of the skin's surface. The palmitoyl portion is added to improve the peptide's compatibility with oil-containing products and its delivery onto the skin.

What does Palmitoyl Hexapeptide-14 do in skincare?

Palmitoyl Hexapeptide-14 is a synthetic peptide used as a skin-conditioning and signaling-type active. The palmitoyl (fatty acid) portion helps it blend into and spread through oil-containing formulas and reach the skin surface. It is generally included to support the overall look and feel of the skin.

Is Palmitoyl Hexapeptide-14 safe?

Palmitoyl peptides are commonly used in cosmetics and are generally considered safe at the low concentrations used in finished formulas. As with any active, people with sensitive skin may wish to patch test a new product first. This is not medical advice, so consult a qualified professional with specific concerns.

Is Palmitoyl Hexapeptide-14 natural or synthetic?

It is a synthetic ingredient. The peptide chain is made through controlled synthesis and then bonded to palmitic acid, a fatty acid, to improve its compatibility with formulas. It is not a botanical extract.

Sunscreens with Palmitoyl Hexapeptide - 14

We rate 7 sunscreens that contain it:

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