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Palmitoyl Tripeptide-38

What Palmitoyl Tripeptide-38 is & what it does

Palmitoyl Tripeptide-38 is a synthetic peptide attached to a palmitic acid chain, used in skincare formulas as a skin-conditioning and signaling ingredient. The fatty acid portion helps it penetrate the skin's surface, where the peptide is intended to support a smoother, firmer appearance. A notable property is its common use in anti-aging products marketed for their effect on the look of fine lines.

What does Palmitoyl Tripeptide-38 do in skincare?

Palmitoyl Tripeptide-38 is a peptide-based skin-conditioning ingredient. The attached fatty acid helps it reach the skin's surface, where the peptide is intended to support a smoother, firmer appearance. It is commonly included in anti-aging formulas aimed at the look of fine lines.

Is Palmitoyl Tripeptide-38 safe?

Palmitoyl Tripeptide-38 is used in cosmetic formulas at low concentrations and is generally considered safe for that use. It is intended for external application in finished products. If you have specific sensitivities or concerns, it is best to consult a dermatologist.

Is Palmitoyl Tripeptide-38 natural or synthetic?

Palmitoyl Tripeptide-38 is synthetic. It is a lab-made peptide of three amino acids joined to a palmitic acid chain. It is produced through controlled synthesis rather than extracted from a natural source.

Sunscreens with Palmitoyl Tripeptide-38

We rate 23 sunscreens that contain it, showing the top 10 by overall score:

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