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SH-Polypeptide-1

What SH-Polypeptide-1 is & what it does

SH-Polypeptide-1 is a synthetic, biotechnology-derived peptide, the "SH" prefix indicating a synthetic human-identical sequence produced by fermentation rather than extracted from skin. In skincare it is used as a skin-conditioning agent and is commonly associated with growth-factor type ingredients aimed at supporting the look of skin. It is used at very low concentrations as an active-style component.

What does SH-Polypeptide-1 do in skincare?

SH-Polypeptide-1 is a synthetic peptide used as a skin-conditioning agent, often associated with growth-factor style ingredients meant to support the look of skin. It is included to help skin appear smoother and more conditioned. It is used at very low concentrations as an active-style component.

Is SH-Polypeptide-1 safe?

SH-Polypeptide-1 is a biotechnology-derived peptide used in skincare at very low levels and is generally considered safe in cosmetic use. As a peptide-based ingredient it is usually chosen for its conditioning role. If you have specific concerns, consult a dermatologist.

Is SH-Polypeptide-1 natural or synthetic?

It is synthetic in the sense that it is produced through biotechnology, typically by fermentation, to create a human-identical peptide sequence rather than being extracted from skin. The "SH" prefix signals this synthetic human-identical origin. Because no animal tissue is used, it is generally considered suitable for vegan formulas, though brands may confirm their specific process.

Sunscreens with SH-Polypeptide-1

We rate 10 sunscreens that contain it:

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