ISIS PHARMA Uveblock Clean Derm SPF 30 Cream
67/100 overall score
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About this sunscreen
ISIS PHARMA Uveblock Clean Derm SPF 30 Cream is a chemical-led sunscreen with a small mineral component, using Ethylhexyl Methoxycinnamate, Octocrylene, Butyl Methoxydibenzoylmethane, and Titanium Dioxide. It has a balanced finish, low white cast, and a lightweight feel, with a medium sting risk to keep in mind near the eyes. Protection is rated good. The 67.1/100 score reflects the older filter set, placing it in the middle of the field.
Ingredient & SPF scores
☀️
UV protection
Good
57
- +18 Ethylhexyl Methoxycinnamate at #3, UV filter
- +31.4 Titanium Dioxide at #4, UV filter (UVA1 +4.8)
- +7.6 Ethylhexyl Salicylate at #5, UV filter
- +28.5 Butyl Methoxydibenzoylmethane at #7, UV filter (UVA1 +15.2)
- +12.8 Octocrylene at #11, UV filter
- −18.4 UVB coverage saturated
- −4.9 UVA2 coverage saturated
- ×0.75 Avobenzone + octinoxate degrade each other in sunlight
- +1 Label claims (SPF 30)
☢️
Health safety
Medium
50
- +100 Starting score
- −36 Octinoxate at #3 (regulatory/evidence concern)
- −10.5 Octocrylene at #11, stacked (regulatory/evidence concern)
- −3.5 Avobenzone at #7, stacked (regulatory/evidence concern)
🤧
Allergens
Low
97
- +100 Starting score
- −3 Photoallergen-tail UV filters (Octocrylene)
👻
White cast
Low
85
- +100 Starting score
- −17.5 Titanium Dioxide at #4 (nano)
- +1.7 PHSA dispersant, fights agglomeration
- +1.1 Coated minerals (Alumina)
🔥
Eye sting
Medium
55
- +100 Starting score
- −16 Avobenzone at #7, migrates into eyes with sweat
- −7 Octocrylene at #11, migrates into eyes with sweat
- −16 Octinoxate at #3, migrates into eyes with sweat
- −6 Octisalate at #5, migrates into eyes with sweat
🪨
Heavy feel
Low
83
- +100 Starting score
- −16 Titanium Dioxide at #4
- −1 Paraffinum Liquidum at #18, heavy oil
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Fungal acne
Low
89
- +100 Starting score
- −9 1 long-chain (C12+) esters that feed Malassezia (Sodium Stearoyl Glutamate)
- −2 1 ubiquitous fatty ingredients (Stearic Acid), weak Malassezia signal
👕
Fabric stains
High
20
- +100 Starting score
- −45 Avobenzone at #7, reacts with iron in wash water into rust-yellow stains
- −15 Octocrylene at #11, co-stains alongside avobenzone
- −10 Avobenzone + Octocrylene, the classic staining pair
- −10 Titanium Dioxide at #4, white marks, worst on dark fabric (washable)
💧
Moisture
Balanced
LightNourishing
- ← 6 3 sebum-absorbing powders (Silica, Aluminium Starch Octenylsuccinate, Methyl Methacrylate Crosspolymer)
- → 4 Glycerin at #10, the anchor humectant
✨
Finish
Balanced
MatteDewy
- ← 5 3 sebum-absorbing powders (Methyl Methacrylate Crosspolymer, Aluminium Starch Octenylsuccinate, Silica)
- ← 2 1 dry-touch emollients reduce greasy shine (Dicaprylyl Carbonate)
- → 9 1 emollient lipids (C12-15 Alkyl Benzoate)
- → 1 Occlusives seal moisture in (Paraffinum Liquidum)
💄
Makeup base
Okay
PillsPrimer
- → 3 1 soft-focus powders in moderation
- → 5 Dry-touch esters, smooth fast-absorbing base
- ← 0.5 Gel polymers prone to pilling under friction (Ammonium Acryloyldimethyltaurate/VP Copolymer)
- ← 1 Occlusives/waxes float the foundation
- ← 3 High mineral load at #4 greys under foundation (nano)
🌊
Water resistance
Not resistant
Non-water-resistantWater-resistant
Nothing flagged in the ingredient list.
How we rate water resistance →Full ingredient list (29)
What each ingredient does and how it moves each rating: green helps, red hurts, ↑ / ↓ give the direction, and ← / → shift a slider toward its ends (finish, moisture, makeup base). Auto-derived from our scoring rules and the ingredient's position.
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1 Water
Solvent base, the water phase
-
Emollient, softens and smooths skin
- 9 → dewy emollient lipid
-
Legacy UV filter (Octinoxate), high in the list, a primary filter
- ↑ 18 UV protection
- ↑ 16 migrates into eyes with sweat
-
Mineral UV filter (Titanium Dioxide)
- ↑ 31.4 UV protection, incl. long-UVA (UVA1)
- ↑ 10 white marks, worst on dark fabric (washable)
- pills ← 3 High mineral load greys under foundation (nano)
-
Legacy UV filter (Octisalate)
- ↑ 7.6 UV protection
- ↑ 6 migrates into eyes with sweat
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Emollient, softens and smooths skin
- matte ← 2 dry-touch emollient, anti-shine
-
Legacy UV filter (Avobenzone)
- ↑ 28.5 UV protection, incl. long-UVA (UVA1)
- ↓ 3.5 stacked (regulatory/evidence concern)
- ↑ 16 migrates into eyes with sweat
- ↑ 45 reacts with iron in wash water into rust-yellow stains
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Emulsifier, keeps oil and water blended
-
Mattifying powder, absorbs oil and blurs the finish
- light ← 3 sebum-absorbing powder
- matte ← 3 sebum-absorbing powder
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10 Glycerin
Humectant, pulls water into the skin
- 4 → nourishing the anchor humectant
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11 Octocrylene
Legacy UV filter (Octocrylene), low in the list, likely a minor contributor
- ↑ 12.8 UV protection
- ↓ 10.5 stacked (regulatory/evidence concern)
- ↑ 7 migrates into eyes with sweat
- ↑ 15 co-stains alongside avobenzone
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Emulsifier, keeps oil and water blended
-
Thickener and texture, structures the gel or cream
-
Emulsifier, keeps oil and water blended
- ↑ 9 feeds malassezia
-
Mattifying powder, absorbs oil and blurs the finish
- light ← 1.5 sebum-absorbing powder
- matte ← 1 sebum-absorbing powder
-
Preservative, keeps the formula from spoiling
-
17 Alumina
Supporting ingredient
-
Occlusive, seals moisture into the skin
- ↑ 1 heavy oil
- 1 → dewy occlusive
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Supporting ingredient
-
20 Stearic Acid
Emollient, softens and smooths skin
- ↑ 2 minor malassezia feeder
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Emollient, softens and smooths skin
-
Chelator, binds stray metal ions to keep the formula stable
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Emollient, softens and smooths skin
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Chelator, binds stray metal ions to keep the formula stable
-
Antioxidant, protects the formula and skin
-
Supporting ingredient
-
27 Silica
Mattifying powder, absorbs oil and blurs the finish
- light ← 1.5 sebum-absorbing powder
- matte ← 1 sebum-absorbing powder
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28 BHT
Antioxidant, protects the formula and skin
-
29 Tocopherol
Antioxidant, protects the formula and skin
Is the ISIS PHARMA Uveblock Clean Derm SPF 30 Cream mineral or chemical?
It is chemical-led with a small mineral component. It uses Ethylhexyl Methoxycinnamate, Octocrylene, and Butyl Methoxydibenzoylmethane along with some Titanium Dioxide.
Does the ISIS PHARMA Uveblock Clean Derm SPF 30 Cream sting the eyes?
Sting risk is rated medium, so some sensitivity near the eyes is possible. Apply carefully around the immediate eye area.
Is it good?
It is a middle-of-the-road option. Protection is rated good, but the older filter set gives it a 67.1/100 score.