ISIS PHARMA Uveblock Invisible Cream SPF 80
61/100 overall score
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About this sunscreen
ISIS PHARMA Uveblock Invisible Cream SPF 80 is a chemical (older-generation) sunscreen combining Octinoxate, Octocrylene and Avobenzone with Zinc Oxide and Titanium Dioxide. Despite the "invisible" name it tends to leave a visible white cast and feels moderately heavy, though it does not commonly sting and has a low pore-clogging profile. The SPF 80 gives good protection. With a score of 60.8 out of 100, it is a high-SPF option whose noticeable cast and dated filter base keep its overall rating moderate.
Ingredient & SPF scores
☀️
UV protection
Good
69
- +41 Zinc Oxide at #2, UV filter (UVA1 +18)
- +18 Ethylhexyl Methoxycinnamate at #3, UV filter
- +15.2 Octocrylene at #4, UV filter
- +24 Butyl Methoxydibenzoylmethane at #8, UV filter (UVA1 +12.8)
- +26.4 Titanium Dioxide at #9, UV filter (UVA1 +4)
- −21.2 UVB coverage saturated
- −13.6 UVA2 coverage saturated
- ×0.75 Avobenzone + octinoxate degrade each other in sunlight
- +2 Label claims (SPF 80)
☢️
Health safety
Medium
40
- +100 Starting score
- −36 Octinoxate at #3 (regulatory/evidence concern)
- −10.5 Octocrylene at #4, stacked (regulatory/evidence concern)
- −3.5 Avobenzone at #8, stacked (regulatory/evidence concern)
- −10 Propylparaben at #26, endocrine-scrutinized preservative
🤧
Allergens
Low
89
- +100 Starting score
- −8 Sensitizing preservatives (Diazolidinyl Urea)
- −3 Photoallergen-tail UV filters (Octocrylene)
👻
White cast
High
26
- +100 Starting score
- −55 Zinc Oxide at #2
- −15 Titanium Dioxide at #9
- −10 Zinc Oxide + Titanium Dioxide together
- +5.6 Coated minerals (Triethoxycaprylylsilane)
🔥
Eye sting
Low
61
- +100 Starting score
- −8 Avobenzone at #8, migrates into eyes with sweat
- −15 Octocrylene at #4, migrates into eyes with sweat
- −16 Octinoxate at #3, migrates into eyes with sweat
🪨
Heavy feel
Medium
47
- +100 Starting score
- −40 Zinc Oxide at #2
- −6 Titanium Dioxide at #9
- −2 Tribehenin at #18, wax film
- −5 Cetyl Alcohol at #7, rich gel-network thickener
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Fungal acne
Medium
50
- +100 Starting score
- −50 6 long-chain (C12+) esters that feed Malassezia (Glyceryl Stearate, Glyceryl Dibehenate, PEG-75 Stearate)
👕
Fabric stains
High
17
- +100 Starting score
- −38 Avobenzone at #8, reacts with iron in wash water into rust-yellow stains
- −15 Octocrylene at #4, co-stains alongside avobenzone
- −10 Avobenzone + Octocrylene, the classic staining pair
- −15 Zinc Oxide at #2, white marks, worst on dark fabric (washable)
- −5 Both minerals present, heavier deposit
💧
Moisture
Balanced
LightNourishing
- ← 1 Volatile carriers flash off, leaving a dry finish
- ← 5 Zinc Oxide at #2, mild sebum absorbent
- → 4 Glycerin at #12, the anchor humectant
- → 1 1 fatty-alcohol emollients (Cetyl Alcohol)
✨
Finish
Balanced
MatteDewy
- ← 1 Volatile carriers flash off, leaving a dry finish
💄
Makeup base
Okay
PillsPrimer
- → 3 Primer-style base, volatile silicones and dimethicone slip
- ← 15 High mineral load at #2 greys under foundation
🌊
Water resistance
Not resistant
Non-water-resistantWater-resistant
- +2 1 water-locking waxes
Full ingredient list (27)
What each ingredient does and how it moves each rating: green helps, red hurts, ↑ / ↓ give the direction, and ← / → shift a slider toward its ends (finish, moisture, makeup base). Auto-derived from our scoring rules and the ingredient's position.
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1 Water
Solvent base, the water phase
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Mineral UV filter (Zinc Oxide), high in the list, a primary filter
- ↑ 41 UV protection, incl. long-UVA (UVA1)
- ↑ 15 white marks, worst on dark fabric (washable)
- light ← 5 mild sebum absorbent
- pills ← 15 High mineral load greys under foundation
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Legacy UV filter (Octinoxate), high in the list, a primary filter
- ↑ 18 UV protection
- ↑ 16 migrates into eyes with sweat
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Legacy UV filter (Octocrylene)
- ↑ 15.2 UV protection
- ↓ 10.5 stacked (regulatory/evidence concern)
- ↑ 15 migrates into eyes with sweat
- ↑ 15 co-stains alongside avobenzone
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Supporting ingredient
-
Emollient, softens and smooths skin
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Fatty alcohol, an emollient and thickener, not the drying kind
- ↑ 5 rich gel-network thickener
- 1 → nourishing fatty-alcohol emollient
-
Legacy UV filter (Avobenzone), low in the list, likely a minor contributor
- ↑ 24 UV protection, incl. long-UVA (UVA1)
- ↓ 3.5 stacked (regulatory/evidence concern)
- ↑ 8 migrates into eyes with sweat
- ↑ 38 reacts with iron in wash water into rust-yellow stains
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Mineral UV filter (Titanium Dioxide), low in the list, likely a minor contributor
- ↑ 26.4 UV protection, incl. long-UVA (UVA1)
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Humectant, pulls water into the skin
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Emulsifier, keeps oil and water blended
- ↑ 14 feeds malassezia
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12 Glycerin
Humectant, pulls water into the skin
- 4 → nourishing the anchor humectant
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Volatile silicone, flashes off for a light finish
- light ← 1 volatile carrier, flashes off
- matte ← 1 volatile carrier, flashes off
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Emulsifier, keeps oil and water blended
- ↑ 9 feeds malassezia
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Emulsifier, keeps oil and water blended
- ↑ 9 feeds malassezia
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16 Ceteth-20
Emulsifier, keeps oil and water blended
- ↑ 9 feeds malassezia
-
Emollient, softens and smooths skin
-
18 Tribehenin
Emollient, softens and smooths skin
- ↑ 2 wax film
- ↑ 2 wax water lock
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19 Xanthan Gum
Thickener and texture, structures the gel or cream
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20 Steareth-20
Emulsifier, keeps oil and water blended
- ↑ 9 feeds malassezia
-
Humectant, pulls water into the skin
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Emulsifier, keeps oil and water blended
- ↑ 9 feeds malassezia
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Supporting ingredient
-
24 Dimethiconol
Emollient, softens and smooths skin
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Preservative, keeps the formula from spoiling
-
Preservative, keeps the formula from spoiling
- ↓ 10 endocrine-scrutinized preservative
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27 BHT
Antioxidant, protects the formula and skin
Does ISIS PHARMA Uveblock Invisible Cream really go on invisible?
Despite the name, its white cast is rated high, so it can leave a visible whitish layer. The mineral zinc and titanium in the formula contribute to this, especially on deeper skin tones.
What SPF is ISIS PHARMA Uveblock cream?
It is SPF 80, a very high label rating that gives good protection. It is a high-coverage option, though the actual benefit over SPF 50 is generally small in real-world use.
Is ISIS PHARMA Uveblock Invisible Cream good?
It scores 60.8 out of 100, a moderate result. The high SPF and low pore-clogging risk are pluses, but the visible white cast and dated filter base keep its overall rating in the middle.